abstract：:To study the haemodynamic and neurohumoral effects of nisoldipine (2 X 10 mg) vs captopril (3 X 25 mg), 24 patients with heart failure (New York Heart Association class II and III) due to coronary artery disease were treated in a randomized double-blind trial over 3 months. Both drugs were well tolerated. Clinical sta...

journal_title：European heart journal

authors： Schofer J,Hobuss M,Aschenberg W,Tews A

更新日期：1990-08-01 00:00:00

abstract：:For clinical prognosis, LV function is best described in terms of ejection fraction (EF) or end-systolic volume (ESV). Because deterioration of LV function is the most important adverse prognostic factor for patients after recovery from myocardial infarction, any agent which improves function should improve long-term ...

journal_title：European heart journal

authors： Norris RM,White HD

更新日期：1990-08-01 00:00:00

abstract：:The effects of the calcium antagonist, diltiazem (D), on left ventricular (LV) response to postextrasystolic potentiation (PESP) were investigated in 15 coronary artery disease patients. Several haemodynamic and LV function parameters, as well as regional wall kinetics, were analysed. During LV angiography, which was ...

journal_title：European heart journal

authors： Di Donato M,Maioli M,Marchionni N,Barletta GA,Fantini F

更新日期：1990-07-01 00:00:00

abstract：:Electrophysiological properties were studied in a heterotopic heart transplant model developed in 44 dogs (Group I). Cycle length was 359.5 +/- 55.2 ms in the recipient heart and 500.9 +/- 77.9 ms in the donor heart (P less than 0.001). Sinoatrial conduction time was 38.6 +/- 13.6 ms in the recipient heart and 38.6 +/...

journal_title：European heart journal

authors： Alvarez L,Escudero C,Alzueta J,Silva L,Márquez-Montes J,Castillo-Olivares JL

更新日期：1990-06-01 00:00:00

abstract：:The diagnosis of prosthetic valve thrombosis (PVT) may be difficult in cases without valve obstruction. The aim of this study was to evaluate the diagnostic accuracy of 111indium-labelled autologous platelet imaging in the detection of PVT. We studied 41 patients with 45 prostheses, mechanical (37) or biological (8), ...

journal_title：European heart journal

authors： Acar J,Vahanian A,Dorent R,Fauchet M,Mundler O,Michel PL,Roger V,Cormier B

更新日期：1990-05-01 00:00:00

abstract：:Myocardial relaxation is an energy-dependent process. Indeed, adenosine triphosphate (ATP) is required to pump free myoplasmic calcium back into the sarcoplasmic reticulum. It is also necessary to extrude the calcium ions which enter the cell during the plateau phase of the action potential. The calcium-sodium exchang...

journal_title：European heart journal

authors： Pouleur H

更新日期：1990-05-01 00:00:00

abstract：:The effects of xamoterol 0.2 mg kg-1 i.v. and placebo on left ventricular function at rest and on exercise were compared in patients with left ventricular dysfunction due to ischaemic heart disease. Improvements were seen in systolic and diastolic function at rest, and at up to 50% of maximal exercise, without evidenc...

journal_title：European heart journal

authors： de Feyter PJ,Serruys PW

更新日期：1990-04-01 00:00:00

abstract：:Sequential alterations of left ventricular volumes and haemodynamics were studied in 29 patients between 4 days and 4 weeks after myocardial infarction. Left ventricular volume was determined by single photon emission computerized tomography (SPECT), infarct size by creatine kinase (CK) analysis, angiography and thall...

journal_title：European heart journal

authors： Gaudron P,Eilles C,Ertl G,Kochsiek K

更新日期：1990-04-01 00:00:00

abstract：:To compare the blood pressure (BP) changes during a long-distance run with those during bicycle ergometry, nine normotensive and 18 hypertensive joggers were studied by means of ambulatory intra-arterial monitoring. In all subjects the ergometric test caused a progressive increase in systolic and little change in dias...

journal_title：European heart journal

authors： Palatini P,Mos L,Mormino P,Munari L,Del Torre M,Valle F,Scaldalai E,Pessina AC

更新日期：1990-04-01 00:00:00

abstract：:This case report describes the delayed improvement of left ventricular function by recanalization of an occluded coronary artery in a patient with intractable heart failure and three-vessel disease. The left anterior descending coronary artery was occluded distal to the first septal branch, the dominant right coronary...

journal_title：European heart journal

authors： Klein HH,Neuhaus KL

更新日期：1990-03-01 00:00:00

abstract：:We have conducted a randomized, double-blind, placebo-controlled multicentre trial of oral isosorbide 5-mononitrate (ISMN) in 360 patients with suspected acute myocardial infarction. Patients were stratified prior to analysis according to the presence or absence of left ventricular failure on admission. ISMN caused a ...

journal_title：European heart journal

authors： Fitzgerald LJ,Bennett ED

更新日期：1990-02-01 00:00:00

abstract：:We performed echocardiographic evaluation of 20 male veteran endurance runners (mean age 56 +/- 7 years) and compared them with a group of age-matched controls. All the runners had run at least 25 miles per week for more than 25 years. Although only four athletes showed voltage ECG evidence of left ventricular hypertr...

journal_title：European heart journal

authors： Northcote RJ,McKillop G,Todd IC,Canning GP

更新日期：1990-01-01 00:00:00

abstract：:Recombinant tissue-type plasminogen activator (rt-PA) is presently used for the treatment of different clinical entities, mostly myocardial infarction. Its use for treatment of thrombotic dysfunction of prosthetic cardiac valves is more recent and has been only rarely reported. A 33-year-old woman with a St Jude Medic...

journal_title：European heart journal

authors： Prieto Palomino MA,Ruiz de Elvira MJ,Sanchez Llorente F,Torrado E,Castillo JL,Gonzalez de Vega N,Garijo Galve A

更新日期：1989-12-01 00:00:00

abstract：:During urgent cardiac catheterization total occlusion of a severe left main coronary artery stenosis occurred, leading to profound cardiogenic shock. The patient survived, after prompt left main coronary angioplasty was performed, followed by emergency coronary bypass surgery. ...

journal_title：European heart journal

authors： Groves PH,Ikram S,Hayward MW,Hall RJ

更新日期：1989-12-01 00:00:00

abstract：:Earlier studies have shown that return to work following PTCA is frequent; however PTCA is now performed in patients with more extensive coronary artery disease. The present study was designed to compare the vocational outcome of patients who underwent PTCA in 1980-1982 with that of patients who underwent the procedur...

journal_title：European heart journal

authors： Danchin N,Juilliere Y,Selton-Suty C,Vaillant G,Pernot C,Gilgenkrantz JM,Villemot JP,Mathieu P,Cherrier F

更新日期：1989-12-01 00:00:00

abstract：:In a pilot study, a prophylactic regimen including ciprofloxacin and amphotericin B was applied in 102 consecutive patients on artificial respiration for greater than or equal to 5 days to prevent respiratory tract infection with aerobic Gram-negative bacilli. Ciprofloxacin was given twice a day, as 500 mg through a g...

journal_title：European heart journal

authors： Haverkorn MJ

更新日期：1989-12-01 00:00:00

abstract：:Although indicated by several experimental studies, the presence of a renin-angiotensin system has not been demonstrated in the human heart. The influence of a local renin-angiotensin system on the coronary vessels may be difficult to establish after oral or intravenous administration of an angiotensin converting-enzy...

journal_title：European heart journal

authors： Foult JM,Tavolaro O,Antony I,Nitenberg A

更新日期：1989-11-01 00:00:00

abstract：:In isolated atherosclerotic human coronary arteries endothelium-dependent vascular relaxation is abolished with acetylcholine whereas another EDRF-dependent vasodilator, substance P, still produces significant relaxation. To study further these in vitro findings, graded doses of acetylcholine and substance P, which pr...

journal_title：European heart journal

authors： Bossaller C,Hehlert-Friedrich C,Jost S,Rafflenbeul W,Lichtlen P

更新日期：1989-11-01 00:00:00

abstract：:Five, ten and fifteen min after sublingual administration of 10mg isosorbide dinitrate (ISDN) in chewing capsules, in 10 patients with coronary artery disease, ISDN plasma levels were correlated with the dilation of epicardial coronary arteries as well as with changes in aortic blood pressure and heart rate. Due to th...

journal_title：European heart journal

authors： Jost S,Rafflenbeul W,Knop I,Bossaller C,Gulba D,Hecker H,Lippolt P,Lichtlen PR

更新日期：1989-11-01 00:00:00

abstract：:To analyse quantitatively a coronary arterial segment from a cineangiogram, an end-diastolic or neighbouring frame is usually selected. However, different cardiologists may select other (although usually neighbouring) frames, even when the same selection criteria are followed. It is also possible that the frames are s...

journal_title：European heart journal

authors： Reiber JH,van Eldik-Helleman P,Kooijman CJ,Tijssen JG,Serruys PW

更新日期：1989-11-01 00:00:00

abstract：:The efficacy of sustained-release diltiazem (diltiazem-SR) 120 mg b.i.d. was compared with metoprolol 100 mg b.i.d. in 12 patients with stable angina. Following a 1-week placebo period, patients received diltiazem-SR or metoprolol in two 3-week treatment periods, in a randomized double-blind crossover design. Total ex...

journal_title：European heart journal

authors： Posma JL,van Dijk RB,Lie KI

更新日期：1989-10-01 00:00:00

abstract：:At the moment, the most reliable method for diagnosing right ventricular dysplasia is considered to be angiography. Morphological alterations such as the presence of akinetic/dyskinetic areas, aneurysmatic dilatations and deep anteroapical fissuring, not necessarily associated with an increase in ventricular volume, a...

journal_title：European heart journal

authors： Chiddo A,Locuratolo N,Gaglione A,Bortone A,Troito G,Musci S,Grimaldi N,Rizzon P

更新日期：1989-09-01 00:00:00

abstract：:Intracranial mycotic aneurysms (IMA) occur in 1-3% of all infective endocarditis. Although spontaneous resolution was evidenced on serial angiograms in many asymptomatic cases, the prognosis, if they rupture, is reported to be worse and partly contingent on the therapeutic approach. Among 12 patients (six acute and si...

journal_title：European heart journal

authors： Monsuez JJ,Vittecoq D,Rosenbaum A,Goujon C,Wolff M,Witchitz S,Modai J

更新日期：1989-09-01 00:00:00

abstract：:Two-dimensional echocardiography (2D echo) and Doppler were performed in a group of patients who had a high probability of having right ventricular (RV) dysplasia (left bundle branch block arrhythmias, no signs of cardiopulmonary diseases) and in a group of age-matched normals. 2D echo showed RV morphofunctional abnor...

journal_title：European heart journal

authors： Iliceto S,Izzi M,De Martino G,Rizzon P

更新日期：1989-09-01 00:00:00

abstract：:In a 2-D model of anisotropy, created by freezing the intramural and endocardial layers of a Langendorf perfused rabbit heart, sustained ventricular tachycardia (VT) with a cycle length of 130 ms and an excitable gap of 30 ms could be initiated by rapid pacing. High resolution mapping (256 points) of the thin survivin...

journal_title：European heart journal

authors： Allessie MA,Schalij MJ,Kirchhof CJ,Boersma L,Huybers M,Hollen J

更新日期：1989-09-01 00:00:00

abstract：:Right ventricular dysplasia (RVD) is a cardiac anomaly characterized by replacement of right ventricular myocardium by adipose and fibrous tissue that was first described at autopsy, and is now being recognized pre-mortem. Sudden death and ventricular arrhythmias are the most common clinical manifestation of the condi...

journal_title：European heart journal

authors： Strain J

更新日期：1989-09-01 00:00:00

abstract：:Intracoronary blood flow velocity measurements with a Doppler balloon catheter and the radiographic assessment of myocardial perfusion with contrast media, before and after the intracoronary administration of papaverine, have previously been used to investigate regional coronary flow reserve. In the present study we a...

journal_title：European heart journal

authors： Serruys PW,Zijlstra F,Laarman GJ,Reiber HH,Beatt K,Roelandt J

更新日期：1989-08-01 00:00:00

abstract：:A right atrial myxoma was detected by cross-sectional echocardiography in a 21-year-old woman with cutaneous lentiginosis. The lentigines were present mainly on the right side of the trunk. ...

journal_title：European heart journal

authors： Göksel S,Kural T

更新日期：1989-08-01 00:00:00

abstract：:Two patients with myocardial bridging of the left anterior descending coronary artery associated with myocardial infarction are described. One of them died from acute cerebral emboli related to cardiac thrombosis in a left ventricular aneurysm. The other died suddenly while sleeping. Both patients were found to have a...

journal_title：European heart journal

authors： Bestetti RB,Costa RS,Zucolotto S,Oliveira JS

更新日期：1989-06-01 00:00:00

abstract：:Cardiac beta-adrenoceptor density and subtype distribution has been determined in different kinds of heart failure. A decrease in cardiac beta-adrenoceptor function appears to be a general phenomenon in all kinds of heart failure. However, cardiac beta 1- and beta 2-adrenoceptors seem to be differentially affected in ...

journal_title：European heart journal

authors： Brodde OE,Zerkowski HR,Borst HG,Maier W,Michel MC

更新日期：1989-06-01 00:00:00

abstract：:In the human heart the beta-adrenergic pathways are the primary means of increasing cardiac performance in response to acute or chronic stress. Control of beta pathway function is achieved by changes in the receptors themselves, and to a lesser degree by adjustments in the inhibitory G protein (Gi). In heart failure m...

journal_title：European heart journal

authors： Bristow MR,Port JD,Hershberger RE,Gilbert EM,Feldman AM

更新日期：1989-06-01 00:00:00

abstract：:The transdermal nitroglycerin patches have been very successful nitrate formulations since their introduction in 1982. Nevertheless, considerable controversy regarding efficacy and tolerance has arisen. Nitroglycerin has multiple mechanisms of action in angina pectoris. Transdermal nitroglycerin in ointment formulatio...

journal_title：European heart journal

authors： Abrams J

更新日期：1989-05-01 00:00:00

abstract：:We describe a case of fatal left ventricular outflow obstruction detected by intraoperative transoesophageal echocardiography. This resulted from acute haematoma formation within the interventricular septum following internal mammary artery grafting to the left anterior descending coronary artery. This unusual case hi...

journal_title：European heart journal

authors： Ettles DF,Firth N,Nair RU,Williams GJ

更新日期：1989-05-01 00:00:00

abstract：:In time domain analysis, detection of late potentials is limited by high pass filtering, noise interference and the necessity to exclude patients with bundle branch block. We therefore used frequency analysis with Fourier transform of multiple segments of the surface electrocardiogram (25 segments, size 80 ms, time sh...

journal_title：European heart journal

authors： Haberl R,Jilge G,Pulter R,Steinbeck G

更新日期：1989-04-01 00:00:00

abstract：:The effects of oral sotalol were compared with the findings obtained in the baseline study of a group of 26 consecutive patients with sustained monomorphic ventricular tachycardia or ventricular fibrillation and inducible ventricular tachycardia. The mean age was 62 years and the mean ejection fraction 33%. The number...

journal_title：European heart journal

authors： Jordaens LJ,Palmer A,Clement DL

更新日期：1989-03-01 00:00:00

abstract：:The utility of high-frequency current applied through the distal electrode of a conventional electrode-catheter for altering atrio-ventricular conduction was studied in 18 anaesthetized dogs. Following adequate unipolar His bundle recording, current was applied over periods of 20-30 s, with an output power of 30 W. Co...

journal_title：European heart journal

authors： Lopez-Merino V,Chorro FJ,Sanchis J,Garcia-Civera R,Such L,Camañas A,Paya R

更新日期：1989-02-01 00:00:00

abstract：:This study has compared the effect on heart rate control of the addition of pindolol 15 mg bd or verapamil 40 mg tds to maintenance digoxin therapy in 12 patients with chronic atrial fibrillation. The study was performed in a randomized cross-over fashion. Treatment effects were assessed by 24-h ambulatory electrocard...

journal_title：European heart journal

authors： James MA,Channer KS,Papouchado M,Rees JR

更新日期：1989-01-01 00:00:00

abstract：:To assess the clinical significance of monitoring during physical training in post-myocardial infarction (MI) patients with asymptomatic exercise-induced ischaemia, we studied 232 patients who were survivors of first recent acute MI and consecutively admitted to the same CCU, who underwent an exercise test (ET) and co...

journal_title：European heart journal

authors： Opasich C,Riccardi G,Assandri J,Calsamiglia G,Forni R,La Rovere M,Cobelli F,De Servi S,Specchia G

更新日期：1988-12-01 00:00:00

abstract：:On the occasion of a routine medical check-up 256 out of 1100 individuals with an accumulation of coronary risk factors were screened for silent myocardial ischaemia by exercise testing and Holter monitoring. Of these individuals 5.5% had a pathological exercise test, 7.4% had ischaemia-like events on the Holter ECG, ...

journal_title：European heart journal

authors： Osterspey A,Treis-Müller I,Günther H,Eggeling T,Siglow C,Gedicke V,Höpp H,Diewitz M,Osterhues H,Hilger HH

更新日期：1988-12-01 00:00:00

abstract：:ST segment monitoring by Holter ECG was conducted in 80 consecutive patients 2-4 weeks before aortocoronary bypass surgery and three weeks and six months after surgery. Preoperatively, all patients were under maximal medical therapy. In 31 out of 80 patients medical therapy could be stopped and thus 24-h ST monitoring...

journal_title：European heart journal

authors： Droste C,Lemmen S,Nitsche R,Betz P,Birnbaum D,Roskamm H

更新日期：1988-12-01 00:00:00